Drugs

Axert

almotriptan

By Ortho-McNeil

What is this medication for?

Almotriptan belongs to the class of medications called 5-hydroxytryptamine receptor agonists. Almotriptan is used for the acute treatment of migraine headaches with or without aura (warning signs that occur before the headache begins). It is not used for prevention of migraine headaches or for treatment of any other type of headache including hemiplegic (one side of the head only), ophthalmoplegic (affecting the eye area only), or basilar (at the bottom of the head only) migraine. Almotriptan works by causing the blood vessels of the head to constrict. Almotriptan eliminates or reduces the symptoms of migraine including headache, nausea, vomiting, and sensitivity to light and sound.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Do not stop taking this medication without consulting your doctor.

What form(s) does this medication come in?

Axert® is available as:

  • tablets
    • 6.25 mg
    • 12.5 mg
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The recommended adult dose of almotriptan is one 6.25 mg or 12.5 mg tablet taken at the first sign of headache. If the headache returns, the dose may be repeated after two hours, but no more than two doses of 12.5 mg tablets should be taken within a 24-hour period (i.e., no more than 25 mg in any 24-hour period). If you have no pain relief after taking the first dose, do not take a second dose without first talking with your doctor. If you need to treat more than four headaches in a 30-day period, talk with your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is very important to use this medication exactly as prescribed by your doctor. Do not use higher doses than those prescribed by your doctor. Do not take a double dose to make up for a missed one.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Who should NOT take this medication?

Almotriptan should not be used by anyone who:

  • is allergic to almotriptan or to any of the ingredients of the medication
  • has a history of heart disease (for example, angina pectoris, a history of heart attack, or silent ischemia)
  • has cerebrovascular (e.g., stroke or transient ischemic attacks) or peripheral vascular syndromes (e.g., ischemic bowel disease, Raynaud's syndrome), valvular heart disease, or an abnormal heart rhythm
  • has uncontrolled high blood pressure
  • has taken another selective serotonin agonist (e.g., sumatriptan, naratriptan) or an ergotamine-containing or ergot-type medication (e.g., dihydroergotamine, methysergide) within the past 24 hours
  • is experiencing a hemiplegic or basilar type migraine
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Last updated: March 2, 2007
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